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chr1_1058531_G_A
For a non-coding regulatory variant the nearest gene by distance is frequently not the regulated gene.
Receptor variant-effect scores
Strongest effect: FXR GoF at normalized 0.711. Impact is high, in the upper range toward the 99th percentile.
ft_head_delta_norm = center bin sum of ALT minus REF on the receptor CHIP_TF head, normalized to the peak population 99th percentile and clipped to [−1, 1]. AhR is reported as exploratory, single replicate.
Cross-annotations
No external database record for this variant. It is a scored in silico saturation SNV.
Mirrored from ClinVar, GTEx, GWAS Catalog, JASPAR/FIMO, gnomAD and phyloP. See Databases.
Region confidence
In receptor peaks: none
Binding motif
Logo for the strongest scoring receptor, FXR. The highlighted column marks the approximate affected base within the response element. External browser: UCSC Genome Browser.